Depression

Medical research has studied in detail the link between depression or depressed mood and hormonal fluctuations. 1 The result: since estrogen, such as estradiol, plays a decisive role in serotonin metabolism, balanced estrogen levels are decisive for well-being and can protect against depression. If estrogen is lacking, so is serotonin, the hormone of happiness. Good mood therefore lacks an important foundation.

Depression is not always linked to hormones

Depression is a serious illness. Between 16 and 20 out of every 100 people suffer from depression at least once in their lives. Women are affected twice as often as men. In recent years, the number of cases has risen considerably. The WHO estimates that today, 5% of adults worldwide suffer from depression. 2

Higher risk of depression during menopause

Studies have shown that changes in the female hormonal balance in the years surrounding menopause significantly increase the risk of depression. During the entire menopause period (around 8 years), women are 2.5 times more likely to suffer from depression than in the preceding years.

To find out whether depression is caused by the menopause or has other causes, consult a doctor. Indeed, treatment depends on a correct diagnosis.

If hormones are balanced, antidepressant therapy is effective.

In the case of hormone deficiency, hormone replacement therapy with bio-identical hormones can help. In cases of severe depression, it can also be combined with an antidepressant.

References

    1. Medical News Today, Beth Sissons, medically reviewed by Nicole Washington, DO, MPH, 17.11.2022, Can hormonal imbalances cause depression? medicalnewstoday.com

    2. WHO, Depressive disorder (depression), https://www.who.int/news-room/fact-sheets/detail/depression